Shuichi Ohkubo Selected Research

TPY-835

9/2005

A novel cinnamic acid derivative that inhibits Cdc25 dual-specificity phosphatase activity.

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Shuichi Ohkubo Research Topics

Disease

13	Neoplasms (Cancer) 12/2021 - 09/2005
2	Breast Neoplasms (Breast Cancer) 06/2020 - 01/2019
2	Lung Neoplasms (Lung Cancer) 01/2020 - 09/2005
1	Glioblastoma (Glioblastoma Multiforme) 10/2021
1	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2021
1	Multiple Myeloma 12/2019
1	Weight Loss (Weight Reduction) 01/2019
1	Body Weight (Weight, Body) 01/2019
1	Gastrointestinal Diseases (Functional Gastrointestinal Disorders) 01/2019
1	Eye Diseases (Eye Disease) 01/2019
1	Toxic Optic Neuropathy 01/2015
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2015
1	Retinoblastoma (Glioblastoma, Retinal) 09/2005

Drug/Important Bio-Agent (IBA)

4	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2015
3	Heat-Shock Proteins (Heat-Shock Protein)IBA 12/2021 - 01/2015
3	TAS4464IBA 01/2021 - 01/2019
3	TAS-116IBA 01/2020 - 01/2015
2	Tyrosine Kinase InhibitorsIBA 12/2021 - 01/2020
2	TAS0728IBA 06/2020 - 01/2019
2	Pharmaceutical PreparationsIBA 06/2020 - 01/2020
2	EnzymesIBA 12/2019 - 01/2019
2	UbiquitinIBA 12/2019 - 01/2019
2	Molecular Chaperones (Chaperone, Molecular)IBA 01/2019 - 01/2015
1	Imatinib Mesylate (Gleevec)FDA Link 12/2021
1	Glial Fibrillary Acidic ProteinIBA 10/2021
1	CRISPR-Associated Protein 9IBA 10/2021
1	Transcription Factors (Transcription Factor)IBA 10/2021
1	Caspase 9IBA 01/2021
1	Thymidylate SynthaseIBA 01/2021
1	TAS-114IBA 01/2021
1	Enzyme Inhibitors (Inhibitors, Enzyme)IBA 01/2021
1	Caspase 8 (Caspase-8)IBA 01/2021
1	dUTP pyrophosphataseIBA 01/2021
1	Fluorouracil (Carac)FDA LinkGeneric 01/2021
1	UracilIBA 01/2021
1	pertuzumabIBA 06/2020
1	Trastuzumab (Herceptin)FDA Link 06/2020
1	Ado-Trastuzumab EmtansineIBA 06/2020
1	AntibodiesIBA 06/2020
1	Immunoconjugates (Immunoconjugate)IBA 06/2020
1	Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA 06/2020
1	glucose-regulated proteinsIBA 01/2020
1	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2019
1	CreatinineIBA 01/2019
1	Ligases (Synthetase)IBA 01/2019
1	Cullin Proteins (Cullins)IBA 01/2019
1	Glutamine (L-Glutamine)FDA Link 04/2010
1	TPY-835IBA 09/2005
1	Retinoblastoma ProteinIBA 09/2005
1	Antineoplastic Agents (Antineoplastics)IBA 09/2005

Therapy/Procedure

3	Therapeutics 06/2020 - 01/2015
2	Oral Administration 01/2019 - 01/2015
1	Drug Therapy (Chemotherapy) 01/2021
1	Aftercare (After-Treatment) 09/2005